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1

Synthesis and Anticancer Activities of Thiazoles, 1,3-Thiazines, and Thiazolidine Using Chitosan-Grafted-Poly(vinylpyridine) as Basic Catalyst

M. Riyadh, Sayed, M. Gomha, Sobhi, A. Mahmmoud, Elmahdi, M. Elaasser, Mahmoud

Journal:

Year:

2015

File:

PDF, 896 KB

2015

2

Synthesis and anticancer activity of arylazothiazoles and 1,3,4-thiadiazoles using chitosan-grafted-poly(4-vinylpyridine) as a novel copolymer basic catalyst

Gomha, Sobhi M., Riyadh, Sayed M., Mahmmoud, Elmahdi A., Elaasser, Mahmoud M.

Journal:

Chemistry of Heterocyclic Compounds

Year:

2015

Language:

english

File:

PDF, 347 KB

english, 2015

3

Facile Synthesis of Pyrazolo[3,4- c ]pyrazoles Bearing Coumarine Ring as Anticancer Agents

Gomha, Sobhi M., Abdel-aziz, Hassan M., El-Reedy, Ahmed A. M.

Journal:

Journal of Heterocyclic Chemistry

Year:

2018

Language:

english

File:

PDF, 516 KB

english, 2018

4

A New Entry for Short and Regioselective Synthesis of [1,2,4]Triazolo[4,3-b][1,2,4]-triazin-7(1H)-ones

Ahmad S. Shawali, Sobhi M. Gomha

Journal:

Advanced Synthesis & Catalysis

Year:

2000

Language:

english

File:

PDF, 46 KB

english, 2000

5

Hydrazonoyl Halides as Precursors for New Fused Heterocycles of 5α-Reductase Inhibitors

Thoraya A. Farghaly, Sobhi M. Gomha, Eman M. H. Abbas, Mohamed M. Abdalla

Journal:

Archiv der Pharmazie

Year:

2012

Language:

english

File:

PDF, 159 KB

english, 2012

6

ChemInform Abstract: A New Entry for Short and Regioselective Synthesis of [1,2,4]Triazolo[4,3-b][1,2,4]-triazin-7(1H)-ones.

Ahmad S. Shawali, Sobhi M. Gomha

Journal:

Year:

2000

File:

PDF, 31 KB

2000

7

ChemInform Abstract: A New Aspect of the Pfitzinger Reaction: Microwave-Assisted Synthesis of the New Heterocyclic Ring System 6-Arylbenzo[4,5]imidazolo[2,1-b]quino[4,3-e]-1,3-thiazin-14-one.

Hatem A. Abdel-Aziz, Sobhi M. Gomha

Journal:

Year:

2009

File:

PDF, 25 KB

2009

8

A novel route to tetracyclic fused tetrazines and thiadiazines

Ikhlass M. Abbas, Sayed M. Riyadh, Magda A. Abdallah, Sobhy M. Gomha

Journal:

Journal of Heterocyclic Chemistry

Year:

2006

Language:

english

File:

PDF, 134 KB

english, 2006

9

Regioselectivity in 1,5-electrocyclization of N-[as-triazin-3-yl]nitrilimines. Synthesis of s-triazolo[4,3-b]-as-triazin-7(8H)-ones

Ahmad Sami Shawali, Sobhi M Gomha

Journal:

Year:

2002

Language:

english

File:

PDF, 198 KB

english, 2002

10

A facile one-pot synthesis of 6,7,8,9-tetrahydrobenzo[4,5]thieno[2,3-d]-1,2,4-triazolo[4,5-a]pyrimidin-5-ones

Journal:

Monatshefte für Chemie - Chemical Monthly

Year:

2009

Language:

english

File:

PDF, 302 KB

english, 2009

11

Novel polyazaheterocyclic systems: Synthesis, antitumor, and antimicrobial activities

Sayed M. Riyadh, Thoraya A. Farghaly, Sobhi M. Gomha

Journal:

Archives of Pharmacal Research

Year:

2010

Language:

english

File:

PDF, 506 KB

english, 2010

12

ChemInform Abstract: Hydrazonoyl Halides as Precursors for New Fused Heterocycles of 5α-Reductase Inhibitors.

Thoraya A. Farghaly, Sobhi M. Gomha, Eman M. H. Abbas, Mohamed M. Abdalla

Journal:

Year:

2012

File:

PDF, 37 KB

2012

13

Synthesis and Antimicrobial Activity of Some New Pyrazoles, Fused Pyrazolo[3,4-d]-pyrimidine and 1,2-Dihydroimidazo-[2,1-c][1,2,4]triazin-6-one Derivatives

Gomha, Sobhi Mohamed, Hassaneen, Huwaida M.E.

Journal:

Year:

2011

Language:

english

File:

PDF, 480 KB

english, 2011

14

Enaminones as Building Blocks in Heterocyclic Preparations: Synthesis of Novel Pyrazoles, Pyrazolo[3,4-d]pyridazines, Pyrazolo[1,5-a]pyrimidines, Pyrido[2,3-d]pyrimidines Linked to Imidazo[2,1-b]thiazole System

M. Gomha, Sobhi, A. Abdel-Aziz, Hatem

Journal:

Year:

2012

Language:

english

File:

PDF, 729 KB

english, 2012

15

Synthesis under Microwave Irradiation of [1,2,4]Triazolo[3,4-b] [1,3,4]thiadiazoles and Other Diazoles Bearing Indole Moieties and Their Antimicrobial Evaluation

Gomha, Sobhi M., Riyadh, Sayed M.

Journal:

Year:

2011

Language:

english

File:

PDF, 560 KB

english, 2011

16

Synthetic Utility of Ethylidenethiosemicarbazide: Synthesis and Anticancer Activity of 1,3-Thiazines and Thiazoles with Imidazole Moiety

M. Riyadh, Sayed, M. Gomha, Sobhi, M. Abbas, Ikhlass, A. Bauomi, Mohammed

Journal:

Year:

2013

Language:

english

File:

PDF, 492 KB

english, 2013

17

ChemInform Abstract: Enaminones as Building Blocks in Heterocyclic Preparations: Synthesis of Novel Pyrazoles, Pyrazolo[3,4-d]pyridazines, Pyrazolo[1,5-a]pyrimidines, Pyrido[2,3-d]pyrimidines Linked to Imidazo[2,1-b]thiazole System.

Gomha, Sobhi M., Abdel-Aziz, Hatem A.

Journal:

Year:

2013

File:

PDF, 41 KB

2013

18

A Convenient Ultrasound-Promoted Synthesis of Some New Thiazole Derivatives Bearing a Coumarin Nucleus and Their Cytotoxic Activity

Gomha, Sobhi M., Khalil, Khaled D.

Journal:

Year:

2012

Language:

english

File:

PDF, 263 KB

english, 2012

19

A Facile Green Synthesis and Anti-Cancer Activity of bis-Arylhydrazononitriles, Triazolo[5,1-c][1,2,4]triazine, and 1,3,4-Thiadiazolines

M. Riyadh, Sayed, M. Gomha, Sobhi, D. Khalil, Khaled, M. El-Zanaty, Ali

Journal:

Year:

2013

Language:

english

File:

PDF, 324 KB

english, 2013

20

3-Amino-8-hydroxy-4-imino-6-methyl-5-phenyl-4,5-dihydro-3H-chromeno [2,3-d ]pyrimidine: An Effecient Key Precursor for Novel Synthesis of Some Interesting Triazines and Triazepines as Potential Anti-Tumor Agents

Badrey, Mohamed G., Gomha, Sobhi M.

Journal:

Year:

2012

Language:

english

File:

PDF, 236 KB

english, 2012

21

Synthesis of a new series of angiotensin II receptor antagonists and antibacterial agents

Farghaly, Thoraya A., Gomha, Sobhi M., Abdalla, Mohamed M.

Journal:

Archives of Pharmacal Research

Year:

2014

Language:

english

File:

PDF, 286 KB

english, 2014

22

Multicomponent reactions for synthesis of bioactive polyheterocyclic ring systems under controlled microwave irradiation

Abbas, Eman M.H., Gomha, Sobhi M., Farghaly, Thoraya A.

Journal:

Arabian Journal of Chemistry

Year:

2014

Language:

english

File:

PDF, 649 KB

english, 2014

23

Synthesis, characterization, and pharmacological evaluation of some novel thiadiazoles and thiazoles incorporating pyrazole moiety as anticancer agents

Gomha, Sobhi M., Salah, Taher A., Abdelhamid, Abdou O.

Journal:

Monatshefte für Chemie - Chemical Monthly

Year:

2015

Language:

english

File:

PDF, 1018 KB

english, 2015

24

Utility of N-aryl 2-aroylhydrazono-propanehydrazonoyl chlorides as precursors for synthesis of new functionalized 1,3,4-thiadiazoles with potential antimicrobial activity

Abdelhamid, Abdou O., Gomha, Sobhi M., Shawali, Ahmad S.

Journal:

Journal of Advanced Research

Year:

2014

Language:

english

File:

PDF, 575 KB

english, 2014

25

Synthesis and Anti-cancer Activity of 1,3,4-Thiadiazole and 1,3-Thiazole Derivatives Having 1,3,4-Oxadiazole Moiety

Dawood, Kamal M., Gomha, Sobhi M.

Journal:

Journal of Heterocyclic Chemistry

Year:

2014

Language:

english

File:

PDF, 207 KB

english, 2014

26

Novel anti-HIV-1 NNRTIs based on a pyrazolo[4,3-d]isoxazole backbone scaffold: design, synthesis and insights into the molecular basis of action

Gomha, Sobhi M., Badrey, Mohamed G., Abdalla, Mohamed M., Arafa, Reem K.

Journal:

Year:

2014

Language:

english

File:

PDF, 515 KB

english, 2014

27

ChemInform Abstract: Multicomponent Synthesis of Novel Penta-Heterocyclic Ring Systems Incorporating a Benzopyranopyridine Scaffold.

Gomha, Sobhi M., Riyadh, Sayed M.

Journal:

Year:

2014

File:

PDF, 25 KB

2014

28

Identification of novel aminothiazole and aminothiadiazole conjugated cyanopyridines as selective CHK1 inhibitors

Gomha, Sobhi M., Abdulla, Mohamed M., Abou-Seri, Sahar M.

Journal:

European Journal of Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 941 KB

english, 2015

29

Novel pyrrole derivatives as selective CHK1 inhibitors: design, regioselective synthesis and molecular modeling

Eldebss, Taha M. A., Gomha, Sobhi M., Abdulla, Mohamed M., Arafa, Reem K.

Journal:

Year:

2015

Language:

english

File:

PDF, 1.22 MB

english, 2015

30

Isoxazolopyrimidinethione and Isoxazolopyridopyrimidinethione Derivatives: Key Intermediates for Synthesis of Novel Fused Triazoles as Potent 5α-Reductase Inhibitors and Anti-Prostate Cancer

Gomha, Sobhi M., Badry, Mohamed G., Abdalla, Mohamed M.

Journal:

Journal of Heterocyclic Chemistry

Year:

2015

Language:

english

File:

PDF, 406 KB

english, 2015

31

Multicomponent Synthesis of Novel Penta-Heterocyclic Ring Systems Incorporating a Benzopyranopyridine Scaffold

Gomha, Sobhi, Riyadh, Sayed

Journal:

Year:

2013

Language:

english

File:

PDF, 188 KB

english, 2013

32

Synthesis of New Pyrazolo[1,5-a]pyrimidine, Triazolo[4,3-a]pyrimidine Derivatives, and Thieno[2,3-b]pyridine Derivatives from Sodium 3-(5-Methyl-1-phenyl-1H-pyrazol-4-yl)-3-oxoprop-1-en-1-olate

Abdelhamid, Abdou O., Gomha, Sobhi M.

Journal:

Journal of Chemistry

Year:

2013

Language:

english

File:

PDF, 347 KB

english, 2013

33

(E)-Ethyl 3-(Dimethylamino)-2-(7,9-diphenyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-2-yl)acrylate

Gomha, Sobhi M., Farghaly, Thoraya A.

Journal:

Year:

2011

Language:

english

File:

PDF, 167 KB

english, 2011

34

Ethyl 3-{2-[(3-Methyl-1H-indol-2-yl)carbonyl]hydrazinylidene}butanoate

Farghaly, Thoraya A., Gomha, Sobhi M.

Journal:

Year:

2012

Language:

english

File:

PDF, 217 KB

english, 2012

35

Ethyl (1,3-diphenyl-1H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)acetate

Farghaly, Thoraya A., Gomha, Sobhi M.

Journal:

Year:

2011

Language:

english

File:

PDF, 192 KB

english, 2011

36

Ecofriendly regioselective one-pot synthesis of chromeno[4,3-d][1,2,4]triazolo[4,3-a]pyrimidine derivatives

Gomha, Sobhi Mohamed, Badrey, Mohamed Gomaa

Journal:

European Journal of Chemistry

Year:

2013

Language:

english

File:

PDF, 457 KB

english, 2013

37

Synthesis of novel indolizine, pyrrolo[1,2-a] quinoline, and 4,5-dihydrothiophene derivatives via nitrogen ylides and their antimicrobial evaluation

Gomha, Sobhi M., Dawood, Kamal M.

Journal:

Journal of Chemical Research

Year:

2014

Language:

english

File:

PDF, 516 KB

english, 2014

38

An efficient synthesis of functionalised 2-(heteroaryl)-3H-benzo[f] chromen-3-ones and antibacterial evaluation

Gomha, Sobhi . M, Abdel-Aziz, Hassan M.

Journal:

Journal of Chemical Research

Year:

2013

Language:

english

File:

PDF, 164 KB

english, 2013

39

A convenient synthesis of some new thiazole and pyrimidine derivatives incorporating a naphthalene moiety

Gomha, Sobhi M., Badrey, Mohamed G.

Journal:

Journal of Chemical Research

Year:

2013

Language:

english

File:

PDF, 140 KB

english, 2013

40

Synthesis and biological evaluation of novel fused triazolo[4,3-$a$] pyrimidinones

ABBAS, Ikhlass, GOMHA, Sobhi, ELNEAIRY, Mohamed, ELAASSER, Mahmoud, MABROUK, Bazada

Journal:

TURKISH JOURNAL OF CHEMISTRY

Year:

2015

Language:

english

File:

PDF, 572 KB

english, 2015

41

Convenient method for synthesis of various fused heterocycles via utility of 4-acetyl-5-methyl-1-phenyl-pyrazole as precursor

MOHAMED GOMHA, Sobhi, SAMI SHAWALI, Ahmad, OSMAN ABDELHAMID, Abdou

Journal:

TURKISH JOURNAL OF CHEMISTRY

Year:

2014

Language:

english

File:

PDF, 256 KB

english, 2014

42

Synthesis and biological evaluation of new pyridines containing imidazole moiety as antimicrobial and anticancer agents

ABBAS, Ikhlass, GOMHA, Sobhi, ELAASSER, Mahmoud, BAUOMI, Mohammed

Journal:

TURKISH JOURNAL OF CHEMISTRY

Year:

2015

Language:

english

File:

PDF, 443 KB

english, 2015

43

Synthesis of new functionalized derivatives of indolo[2,3-e][1,2,4]-triazolo-[4,5-b]-1,2,4-triazine

Gomha, Sobhi, Abdel-Aziz, Hatem

Journal:

Journal of the Serbian Chemical Society

Year:

2013

Language:

english

File:

PDF, 903 KB

english, 2013

44

Correction: Novel pyrrole derivatives as selective CHK1 inhibitors: design, regioselective synthesis and molecular modeling

Eldebss, Taha M. A., Gomha, Sobhi M., Abdulla, Mohamed M., Arafa, Reem K.

Journal:

Year:

2015

Language:

english

File:

PDF, 139 KB

english, 2015

45

Synthesis and Characterization of Bisimidazoles, Bistriazoles, Bisthiadiazoles, and Bisthiazoles from Novel Bishydrazonoyl Dichlorides

Sayed, Abdelwahed R., Gomha, Sobhi M., Farghaly, Thoraya A.

Journal:

Journal of Heterocyclic Chemistry

Year:

2015

Language:

english

File:

PDF, 904 KB

english, 2015

46

Synthesis and Antitumor Activity of 1,3,4-Thiadiazole Derivatives Bearing Coumarine Ring

M. Gomha, Sobhi, M. Abdel-aziz, Hassan

Journal:

Year:

2015

Language:

english

File:

PDF, 792 KB

english, 2015

47

Synthesis and Antihypertensive α-Blocking Activity Evaluation of Thiazole Derivatives Bearing Pyrazole Moiety

Gomha, Sobhi, Khalil, Khaled, Abdel-aziz, Hassan, Abdalla, Mohamed

Journal:

Year:

2015

Language:

english

File:

PDF, 809 KB

english, 2015

48

Synthesis and characterisation of some novel fused thiazolo[3,2-a]pyrimidinones and pyrimido[2,1-b][1,3]thiazinones

Abbas, Ikhlass M., Gomha, Sobhi M., Elaasser, Mahmoud M., Mabrouk, Bazada K. A.

Journal:

Journal of Chemical Research

Year:

2015

Language:

english

File:

PDF, 390 KB

english, 2015

49

Synthesis and Antimicrobial Evaluation of Some Novel Thiazole, 1,3,4-Thiadiazole and Pyrido[2,3-d][1,2,4]triazolo[4,3-a]pyrimidine Derivatives Incorporating Pyrazole Moiety

O. Abdelhamid, Abdou, M. Gomha, Sobhi, S. Shawali, Ahmad

Journal:

Year:

2015

Language:

english

File:

PDF, 489 KB

english, 2015

50

Synthetic routes to benzosuberone-based fused- and spiro- heterocyclic ring systems

Farghaly, Thoraya Abd el Reheem, Gomha, Sobhi, Dawood, KM, Shaaban, Mohamed Rabie

Journal:

Year:

2016

Language:

english

File:

PDF, 1.61 MB

english, 2016